![]() ![]() The incidence of HME is greater in males than females, and the mutations exert incomplete penetrance (Legeai-Mallet et al., ). With a recorded prevalence of 1 in 50,000 in the western population (Schmale et al., ), osteochondromas are the most common benign bone tumors. In 1814, the first HME patient was described by Boyer (Peterson, Ryckx et al., ). ![]() ![]() IntroductionHereditary multiple exostoses (HME), also referred to as multiple exostoses (MO), is an autosomal dominant, inherited skeletal disorder characterized by the development of multiple benign cartilage-capped tumors that appear as outgrowth from the metaphyses of the long bones. Aims: Multiple exostoses (MO), also referred to as hereditary multiple exostoses (HME), is an autosomal dominant inherited skeletal disorder that has been found to be associated with mutations in the EXT1 and EXT2 genes. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |